Our interest in chronic inflammation

There is strong scientific evidence that inflammation contributes to the development of many diseases that arise from lifestyle factors such as obesity, smoking, poor diet and lack of exercise.

There are two forms of inflammation: acute (short term) and chronic (long term). Most people are familiar with acute inflammation; sensations of pain, redness, swelling, and heat that result from an injury or infection, that normally resolve after a few days. Acute inflammation represents an essential survival and regenerative mechanism that helps the body fight off and resolve infection and repair damaged tissue.

In contrast, long term unresolved inflammatory processes are the dark side of inflammation that can be harmful to human health. Long term, or chronic, inflammation is a key risk factor in the development of lifestyle-related diseases17. Long term inflammation may be present for months or years and in the early stages there are usually no symptoms such as pain, redness, swelling and heat.

 

‘Technology has made personalised health information possible; we are making it meaningful’

BEN HERBERT, CHIEF SCIENTIFIC OFFICER

Today, most routine blood tests use conventional venous samples to investigate or confirm diagnosis, as part of health checks or for specific non-disease testing such as during pregnancy.

C-Reactive Protein (CRP) is the most well-known and frequently tested inflammatory protein marker. CRP production in the liver is stimulated by acute events, such as infection, and chronic conditions, such as obesity.

Most CRP testing is used to assess the likelihood of infection. Inflammation levels are not frequently used to assess chronic disease risk or fertility because this would require regular testing of CRP and other inflammatory markers over a time-series to establish an individual’s baseline CRP level.

That’s where we come in.

At Drop, we are developing evidence-based, direct-to-consumer services to help:

  • Women to achieve pre-pregnancy health

  • Men and women to reverse lifestyle disease diagnosis

  • Families to track health and act on early warning of chronic diseases